The Mice Model Market size was estimated at USD 2.1 billion in 2023 and is projected to reach USD 4.3 billion by 2030, exhibiting a compound annual growth rate (CAGR) of 10.80% during the forecast period (2024-2030).

Mice Model Market

Market Summary

The mice model market is an integral segment within the biotechnology and pharmaceutical industries, providing essential tools for biomedical research and drug development. These models are genetically engineered or naturally occurring mice used to study human diseases, test therapeutic interventions, and understand biological processes. The market is characterized by a high degree of specialization, with models designed for oncology, immunology, neurology, and metabolic diseases, among other areas. The reliance on mice models is driven by their genetic similarity to humans, short reproductive cycles, and the ease of genetic manipulation. Companies and research institutions utilize these models to accelerate preclinical studies, reduce drug development costs, and improve the predictability of human responses. The market is supported by continuous advancements in genetic engineering technologies, such as CRISPR-Cas9, which enable the creation of more precise and complex models. Additionally, the growing focus on personalized medicine and the increasing prevalence of chronic diseases are fueling demand for tailored mice models that can mimic specific human conditions. The market landscape includes a mix of academic research, contract research organizations, and pharmaceutical companies, all contributing to a dynamic and competitive environment. Ethical considerations and regulatory frameworks also play a significant role in shaping market practices, ensuring humane treatment and scientific validity. Overall, the mice model market is a cornerstone of modern biomedical research, enabling breakthroughs that translate into improved healthcare outcomes.

Key Highlights

The mice model market is distinguished by several key highlights that underscore its critical role in biotechnology and pharmaceutical research. One significant aspect is the dominance of genetically engineered models, which allow for precise manipulation of genes to study disease mechanisms and therapeutic effects. Technologies like CRISPR-Cas9 have revolutionized the creation of these models, making them more accessible and efficient to produce. Another highlight is the increasing demand for humanized mice models, which are engineered to express human genes or immune systems, providing a more relevant platform for studying human-specific diseases and drug responses. The market is also characterized by a strong focus on oncology research, where mice models are extensively used to test cancer therapies and understand tumor biology. Immunotherapy and infectious disease research are other prominent areas driving market growth. Additionally, the rise of contract research organizations offering specialized mice model services has expanded market accessibility, allowing smaller companies and academic institutions to leverage these tools without maintaining in-house facilities. The integration of advanced imaging and monitoring technologies with mice models enhances data collection and analysis, improving the quality and reliability of research outcomes. Furthermore, ethical advancements and the adoption of the 3Rs principles (Replacement, Reduction, Refinement) are shaping more humane and efficient research practices. These highlights collectively emphasize the market's evolution towards more sophisticated, ethical, and application-specific models that meet the evolving needs of the biomedical community.

Drivers, Opportunities & Restraints

The mice model market is propelled by several drivers, including the increasing prevalence of chronic diseases such as cancer, diabetes, and neurological disorders, which necessitate extensive preclinical research. The growing investment in biomedical research and development by pharmaceutical and biotechnology companies is another major driver, as mice models are indispensable for drug discovery and validation processes. Advancements in genetic engineering technologies, particularly CRISPR-Cas9, have significantly reduced the time and cost associated with creating customized models, further stimulating market growth. Additionally, the rising demand for personalized medicine requires models that can mimic individual patient responses, driving innovation in humanized and patient-derived xenograft models. Opportunities in the market abound, such as the expansion into emerging markets where biomedical research is accelerating, and the increasing outsourcing of research activities to contract organizations. The development of more complex and multifactorial models that can study comorbidities and combination therapies presents another lucrative opportunity. However, the market faces restraints, including ethical concerns and stringent regulatory guidelines governing animal research, which can limit experimentation and increase compliance costs. High maintenance costs associated with housing and handling genetically modified mice also pose challenges. Moreover, the emergence of alternative technologies like organ-on-a-chip and in silico modeling may reduce reliance on animal models in the long term. Despite these restraints, the market continues to grow, driven by the irreplaceable role of mice models in generating critical preclinical data.

Concentration Insights

The mice model market is concentrated among a few key players who dominate due to their extensive portfolios, technological expertise, and global reach. Leading companies include Charles River Laboratories, The Jackson Laboratory, Taconic Biosciences, Envigo, and Janvier Labs. These entities have established strong positions through continuous innovation, strategic acquisitions, and partnerships that enhance their product offerings and geographic presence. Charles River Laboratories, for instance, is renowned for its comprehensive range of models and services, including genetically engineered and humanized mice, supported by robust research and development capabilities. The Jackson Laboratory is a pioneer in providing standardized and custom genetically defined mice, with a significant focus on advancing genetic research. Taconic Biosciences excels in producing precision models for immunology and oncology, catering to the needs of pharmaceutical and academic clients. Envigo offers a diverse array of models and related services, emphasizing quality and reliability. Janvier Labs is noted for its expertise in breeding and supplying genetically modified mice for research purposes. The market concentration is also influenced by the high barriers to entry, such as the need for specialized knowledge, significant capital investment, and compliance with regulatory standards. Smaller players and niche providers often focus on specific model types or regional markets, but the overall landscape remains dominated by these established companies. Their dominance ensures a steady supply of high-quality models but also encourages competition through innovation and customer-centric services.

Type Insights

The mice model market is segmented into various types based on genetic characteristics and applications, with inbred, outbred, genetically engineered, and hybrid models being the primary categories. Inbred models are genetically identical, produced by mating siblings for over 20 generations, which ensures uniformity and reproducibility in research. They are widely used in studies requiring consistent genetic backgrounds, such as immunology and pharmacology. Outbred models are genetically diverse, created through random mating, and are valuable for simulating human population diversity in toxicology and safety testing. Genetically engineered models represent the largest and fastest-growing segment, encompassing knockout, knockin, and transgenic mice. These models are designed to study specific genes or mutations associated with diseases, enabling researchers to investigate causal relationships and therapeutic interventions. CRISPR-Cas9 technology has been instrumental in advancing this segment by allowing precise and efficient genetic modifications. Humanized mice models, a subset of genetically engineered models, are grafted with human cells or tissues to study human-specific biological processes and diseases, particularly in immunology and infectious disease research. Hybrid models, which combine genetic elements from different strains, are used to study complex traits and interactions. Each model type offers distinct advantages, and their selection depends on the research objectives, with genetically engineered models increasingly preferred for their specificity and relevance to human diseases.

Application Insights

Mice models are utilized across a wide range of applications in biomedical research, with oncology, immunology, neurology, and metabolic diseases being the most prominent areas. In oncology, mice models are essential for studying tumor biology, cancer progression, and the efficacy of anticancer therapies. Patient-derived xenograft models, where human tumor tissues are implanted into immunodeficient mice, are particularly valuable for personalized medicine approaches. Immunology research relies heavily on mice models to investigate immune responses, autoimmune diseases, and the development of vaccines and immunotherapies. Humanized immune system models enable the study of human immune cells in vivo, providing insights into infectious diseases like HIV and COVID-19. Neurology applications involve using mice to model neurodegenerative disorders such as Alzheimer's and Parkinson's diseases, as well as psychiatric conditions, helping to identify potential treatments and understand disease mechanisms. Metabolic disease research employs mice models to study diabetes, obesity, and cardiovascular diseases, facilitating the development of drugs that regulate metabolism. Additionally, mice models are used in toxicology and safety pharmacology to assess the adverse effects of new compounds before human trials. The versatility of mice models allows them to be adapted for emerging research areas, such as microbiome studies and rare diseases, underscoring their indispensable role in advancing medical science.

Regional Insights

The mice model market exhibits distinct regional dynamics, with North America leading due to its robust biotechnology and pharmaceutical sectors, high research funding, and concentration of key market players. The United States, in particular, is a major hub, driven by extensive academic and industrial research activities, supportive regulatory frameworks, and advanced healthcare infrastructure. Europe follows closely, with countries like Germany, the United Kingdom, and France being significant contributors. The European market benefits from strong government support for research, well-established ethical guidelines, and a focus on innovative biomedical studies. The Asia-Pacific region is experiencing rapid growth, propelled by increasing investments in healthcare research, rising prevalence of chronic diseases, and expanding pharmaceutical outsourcing. Countries such as China, Japan, and India are emerging as important markets, with growing capabilities in genetic engineering and a surge in contract research organizations. Latin America and the Middle East and Africa are smaller but growing markets, where developing research infrastructure and increasing awareness of advanced research tools are driving adoption. Regional differences in regulatory policies, ethical standards, and research priorities influence market trends, but the global nature of biomedical research ensures that advancements and demands are interconnected across regions.

Company Insights

Key companies in the mice model market include Charles River Laboratories, The Jackson Laboratory, Taconic Biosciences, Envigo, and Janvier Labs, among others. Charles River Laboratories is a global leader, offering a comprehensive portfolio of research models and services, with a strong emphasis on genetically engineered and humanized mice. The company's extensive network and expertise in preclinical research make it a preferred partner for pharmaceutical and biotechnology firms. The Jackson Laboratory is renowned for its vast collection of genetically defined mice, particularly its inbred strains and customized models, supported by cutting-edge genetic research and biobanking services. Taconic Biosciences specializes in precision models for immunology, oncology, and metabolic diseases, providing tailored solutions that enhance research reproducibility and relevance. Envigo focuses on delivering high-quality research models and associated services, with a commitment to animal welfare and scientific excellence. Janvier Labs is known for its efficient breeding and supply of genetically modified mice, catering to the needs of European and international research communities. These companies invest heavily in research and development to innovate new models and improve existing ones, often through collaborations with academic institutions and industry partners. Their competitive strategies include geographic expansion, acquisitions, and enhancing service offerings to maintain market leadership and meet the evolving demands of the biomedical research sector.

Recent Developments

Recent developments in the mice model market reflect ongoing innovation and strategic movements aimed at enhancing research capabilities and market presence. Advances in genetic engineering technologies, particularly CRISPR-Cas9, have continued to streamline the creation of complex models, reducing timeframes and costs while improving precision. Companies are increasingly focusing on developing humanized mice models that better mimic human immune systems and diseases, driven by the growing demand for immuno-oncology and infectious disease research. There has been a notable rise in the use of patient-derived xenograft models for personalized medicine, allowing more accurate prediction of patient responses to therapies. Strategic acquisitions and partnerships have been prominent, such as Charles River Laboratories expanding its portfolio through targeted acquisitions to bolster its genetically engineered model offerings. The Jackson Laboratory has enhanced its digital platforms and data analytics capabilities to support researchers in model selection and data interpretation. Taconic Biosciences has introduced new models for studying the microbiome and its impact on health, tapping into emerging research trends. Additionally, there is increased emphasis on animal welfare and the adoption of the 3Rs principles, leading to the development of more humane and efficient research protocols. These developments collectively aim to address the complex needs of modern biomedical research, ensuring that mice models remain relevant and valuable tools.

Report Segmentation

This report on the mice model market provides a detailed segmentation to offer comprehensive insights into various aspects of the industry. The market is segmented by type, including inbred mice, outbred mice, genetically engineered mice, and hybrid mice. Each type is analyzed in terms of characteristics, applications, and market dynamics. The application segment covers oncology, immunology, neurology, metabolic diseases, toxicology, and others, highlighting the specific uses and demand drivers in each area. Geographically, the market is segmented into North America, Europe, Asia-Pacific, Latin America, and the Middle East and Africa, with regional analysis focusing on key countries, trends, and growth factors. The report also includes segmentation by service, such as breeding, cryopreservation, genetic testing, and quarantine, which are critical support services offered by market players. Additionally, the end-user segment encompasses pharmaceutical and biotechnology companies, academic and research institutions, and contract research organizations, detailing their respective roles and influences in the market. This multidimensional segmentation enables a thorough understanding of the market structure, helping stakeholders identify opportunities and make informed decisions based on specific segments of interest.

FAQs

What are the different types of mice models used in research? Mice models are categorized into inbred, outbred, genetically engineered, and hybrid types. Inbred models are genetically identical, ideal for consistent studies, while outbred models offer genetic diversity. Genetically engineered models, created using technologies like CRISPR, allow precise gene manipulation, and hybrid models combine traits for complex research.

How are genetically engineered mice models created? Genetically engineered mice models are created using advanced technologies such as CRISPR-Cas9, which enables precise editing of genes. This involves inserting, deleting, or modifying specific DNA sequences to mimic human diseases or study gene functions, resulting in models tailored for specific research needs.

What applications are mice models commonly used for? Mice models are extensively used in oncology for cancer research, immunology for studying immune responses, neurology for neurodegenerative diseases, and metabolic diseases like diabetes. They are also employed in toxicology testing and drug development across various therapeutic areas.

Why are humanized mice models important? Humanized mice models are crucial because they incorporate human genes, cells, or tissues, allowing researchers to study human-specific biological processes and diseases. This is particularly valuable in immunology, infectious diseases, and drug testing, where human responses need accurate prediction.

What are the ethical considerations in using mice models? Ethical considerations include ensuring humane treatment, minimizing pain and distress, and adhering to the 3Rs principles: Replacement, Reduction, and Refinement. Regulatory guidelines and oversight committees enforce standards to promote ethical research practices.

Which companies are leading in the mice model market? Leading companies include Charles River Laboratories, The Jackson Laboratory, Taconic Biosciences, Envigo, and Janvier Labs. These firms offer a wide range of models and services, driving innovation and supporting global biomedical research efforts.

Citius Research has developed a research report titled “Mice Model Market Report - Global Industry Analysis, Size, Share, Growth Trends, Regional Outlook, Competitive Strategies and Segment Forecasts 2024 - 2030” delivering key insights regarding business intelligence and providing concrete business strategies to clients in the form of a detailed syndicated report. The report details out the factors such as business environment, industry trend, growth opportunities, competition, pricing, global and regional market analysis, and other market related factors.

Details included in the report for the years 2024 through 2030

• Mice Model Market Potential
• Segment-wise breakup
• Compounded annual growth rate (CAGR) for the next 6 years
• Key customers and their preferences
• Market share of major players and their competitive strength
• Existing competition in the market
• Price trend analysis
• Key trend analysis
• Market entry strategies
• Market opportunity insights

The report focuses on the drivers, restraints, opportunities, and challenges in the market based on various factors geographically. Further, key players, major collaborations, merger & acquisitions along with trending innovation and business policies are reviewed in the report. The Mice Model Market report is segmented on the basis of various market segments and their analysis, both in terms of value and volume, for each region for the period under consideration.

Mice Model Market Segmentation

Regions Covered

• North America
• Latin America
• Europe
• MENA
• Asia Pacific
• Sub-Saharan Africa and
• Australasia

Mice Model Market Analysis

The report covers below mentioned analysis, but is not limited to:

• Overview of Mice Model Market
• Research Methodology
• Executive Summary
• Market Dynamics of Mice Model Market
  • Driving Factors
  • Restraints
  • Opportunities
• Global Market Status and Forecast by Segment A
• Global Market Status and Forecast by Segment B
• Global Market Status and Forecast by Segment C
• Global Market Status and Forecast by Regions
• Upstream and Downstream Market Analysis of Mice Model Market
• Cost and Gross Margin Analysis of Mice Model Market
• Mice Model Market Report - Global Industry Analysis, Size, Share, Growth Trends, Regional Outlook, Competitive Strategies and Segment Forecasts 2024 - 2030
  • Competition Landscape
  • Market Share of Major Players
• Key Recommendations

The “Mice Model Market Report - Global Industry Analysis, Size, Share, Growth Trends, Regional Outlook, Competitive Strategies and Segment Forecasts 2024 - 2030” report helps the clients to take business decisions and to understand strategies of major players in the industry. The report delivers the market driven results supported by a mix of primary and secondary research. The report provides the results triangulated through authentic sources and upon conducting thorough primary interviews with the industry experts. The report includes the results on the areas where the client can focus and create point of parity and develop a competitive edge, based on real-time data results.

Mice Model Market Key Stakeholders

Below are the key stakeholders for the Mice Model Market:

• Manufacturers
• Distributors/Traders/Wholesalers
• Material/Component Manufacturers
• Industry Associations
• Downstream vendors

Mice Model Market Report Scope

COVID-19 Impact Analysis

Like most other markets, the outbreak of COVID-19 had an unfavorable impact on the Mice Model Market worldwide. This report discusses in detail the disruptions experienced by the market, the impact on flow of raw materials, manufacturing operations, production trends, consumer demand and the projected future of this market post pandemic.

The report has helped our clients:

• To describe and forecast the Mice Model Market size, on the basis of various segmentations and geography, in terms of value and volume
• To measure the changing needs of customers/industries
• To provide detailed information regarding the drivers, restraints, opportunities, and challenges influencing the growth of the market
• To gain competitive intelligence and uncover new opportunities
• To analyse opportunities in the market for stakeholders by identifying high-growth segments in Mice Model Market
• To strategically profile key players and provide details of the current competitive landscape
• To analyse strategic approaches adopted by players in the market, such as product launches and developments, acquisitions, collaborations, contracts, expansions, and partnerships

Report Customization

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